{"id":2667,"date":"2025-09-13T04:37:43","date_gmt":"2025-09-13T04:37:43","guid":{"rendered":"https:\/\/surgi-one.com\/main\/?p=2667"},"modified":"2025-09-15T15:59:29","modified_gmt":"2025-09-15T15:59:29","slug":"durasis-dural-graft","status":"publish","type":"post","link":"https:\/\/surgi-one.com\/main\/neurosurgery\/durasis-dural-graft\/","title":{"rendered":"Durasis\u2122 Dural Graft"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"2667\" class=\"elementor elementor-2667\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-425dca9c e-flex e-con-boxed e-con e-parent\" data-id=\"425dca9c\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;boxed&quot;}\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2548787b elementor-widget elementor-widget-text-editor\" data-id=\"2548787b\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.16.0 - 17-10-2023 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<h2>Seal the Deal with an Intact Biological Graft.<\/h2><h1>DURASIS\u2122 DURAL GRAFT<\/h1><p>The Durasis Dural Graft is intended for use as a dura substitute for repairing dura mater. <img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-2672 alignright\" src=\"https:\/\/surgi-one.com\/main\/wp-content\/uploads\/2025\/09\/Durasislogo.png\" alt=\"\" width=\"341\" height=\"72\" srcset=\"https:\/\/surgi-one.com\/main\/wp-content\/uploads\/2025\/09\/Durasislogo.png 341w, https:\/\/surgi-one.com\/main\/wp-content\/uploads\/2025\/09\/Durasislogo-300x63.png 300w\" sizes=\"auto, (max-width: 341px) 100vw, 341px\" \/><\/p><p>Nexsis Biosciences is the exclusive U.S. and Canadian supplier of the Durasis Dural Graft (formerly Cook Biotech\u2019s Biodesign\u00ae Dural Graft).<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-392515d e-flex e-con-boxed e-con e-parent\" data-id=\"392515d\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;boxed&quot;}\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-df21344 e-con-full e-flex e-con e-child\" data-id=\"df21344\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3af3f9b elementor-widget elementor-widget-text-editor\" data-id=\"3af3f9b\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-2678\" src=\"https:\/\/surgi-one.com\/main\/wp-content\/uploads\/2025\/09\/NexsisArtboard-35.webp\" alt=\"\" width=\"458\" height=\"344\" srcset=\"https:\/\/surgi-one.com\/main\/wp-content\/uploads\/2025\/09\/NexsisArtboard-35.webp 458w, https:\/\/surgi-one.com\/main\/wp-content\/uploads\/2025\/09\/NexsisArtboard-35-300x225.webp 300w\" sizes=\"auto, (max-width: 458px) 100vw, 458px\" \/><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b503e52 e-con-full e-flex e-con e-child\" data-id=\"b503e52\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4854754 elementor-widget elementor-widget-text-editor\" data-id=\"4854754\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Durasis\u2122 Dural Graft<\/p><table class=\"table-rules\"><thead><tr class=\"\"><th class=\"elementor-repeater-item-b00a729\">ORDER NUMBER<\/th><th class=\"elementor-repeater-item-d0b03eb\">DESCRIPTION<\/th><th class=\"elementor-repeater-item-f8d00bf\">INSTRUCTIONS FOR USE<\/th><th class=\"elementor-repeater-item-81b5b34\">SIZE<\/th><\/tr><\/thead><tbody><tr class=\" elementor-repeater-item-d3d73c8\"><td class=\"elementor-repeater-item-64edb87\" data-title=\"ORDER NUMBER\"><strong>NXDUR0203<\/strong><\/td><td class=\"elementor-repeater-item-50cadb0\" data-title=\"DESCRIPTION\"><strong>DURASIS DURAL GRAFT<\/strong><br \/>Prior Cook Biodesign<br \/>Order# G32437<\/td><td class=\"elementor-repeater-item-cf508df\" data-title=\"INSTRUCTIONS FOR USE\"><a href=\"https:\/\/surgi-one.com\/main\/wp-content\/uploads\/2025\/09\/Durasis-IFU-052025.pdf\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-2693 aligncenter\" src=\"https:\/\/surgi-one.com\/main\/wp-content\/uploads\/2025\/09\/pdf.png\" alt=\"\" width=\"22\" height=\"22\" \/><\/a><\/td><td class=\"elementor-repeater-item-525a3bb\" data-title=\"SIZE\"><strong>2&#215;3 cm<\/strong><br \/>(0.8&#215;1.2 in)<\/td><\/tr><tr class=\" elementor-repeater-item-b73823b\"><td class=\"elementor-repeater-item-a85cb04\" data-title=\"ORDER NUMBER\"><strong>NXDUR0407<\/strong><\/td><td class=\"elementor-repeater-item-b320e1e\" data-title=\"DESCRIPTION\"><strong>DURASIS DURAL GRAFT<\/strong><br \/>Prior Cook Biodesign<br \/>Order# G31090<\/td><td class=\"elementor-repeater-item-3c00e64\" data-title=\"INSTRUCTIONS FOR USE\"><a href=\"https:\/\/surgi-one.com\/main\/wp-content\/uploads\/2025\/09\/Durasis-IFU-052025.pdf\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-2693 aligncenter\" src=\"https:\/\/surgi-one.com\/main\/wp-content\/uploads\/2025\/09\/pdf.png\" alt=\"\" width=\"22\" height=\"22\" \/><\/a><\/td><td class=\"elementor-repeater-item-d1ffc4b\" data-title=\"SIZE\"><strong>4&#215;7 cm<\/strong><br \/>(1.6&#215;2.8 in)<\/td><\/tr><tr class=\" elementor-repeater-item-fe9e6dd\"><td class=\"elementor-repeater-item-de04405\" data-title=\"ORDER NUMBER\"><strong>NXDUR0710<\/strong><\/td><td class=\"elementor-repeater-item-3f7f00f\" data-title=\"DESCRIPTION\"><strong>DURASIS DURAL GRAFT<\/strong><br \/>Prior Cook Biodesign<br \/>Order# G31091<\/td><td class=\"elementor-repeater-item-3ec2b7b\" data-title=\"INSTRUCTIONS FOR USE\"><a href=\"https:\/\/surgi-one.com\/main\/wp-content\/uploads\/2025\/09\/Durasis-IFU-052025.pdf\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-2693 aligncenter\" src=\"https:\/\/surgi-one.com\/main\/wp-content\/uploads\/2025\/09\/pdf.png\" alt=\"\" width=\"22\" height=\"22\" \/><\/a><\/td><td class=\"elementor-repeater-item-deab568\" data-title=\"SIZE\"><strong>7&#215;10 cm<\/strong><br \/>(2.8&#215;3.9 in)<\/td><\/tr><tr class=\" elementor-repeater-item-845b894\"><td class=\"elementor-repeater-item-9199c1d\" data-title=\"ORDER NUMBER\"><strong>NXDUR0720<\/strong><\/td><td class=\"elementor-repeater-item-d957b27\" data-title=\"DESCRIPTION\"><strong>DURASIS DURAL GRAFT<\/strong><br \/>Prior Cook Biodesign<br \/>Order# G31092<\/td><td class=\"elementor-repeater-item-33ee55a\" data-title=\"INSTRUCTIONS FOR USE\"><a href=\"https:\/\/surgi-one.com\/main\/wp-content\/uploads\/2025\/09\/Durasis-IFU-052025.pdf\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-2693 aligncenter\" src=\"https:\/\/surgi-one.com\/main\/wp-content\/uploads\/2025\/09\/pdf.png\" alt=\"\" width=\"22\" height=\"22\" \/><\/a><\/td><td class=\"elementor-repeater-item-b973db6\" data-title=\"SIZE\"><strong>7&#215;20 cm<\/strong><br \/>(2.8&#215;7.9 in)<\/td><\/tr><\/tbody><\/table>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-97dcced e-flex e-con-boxed e-con e-parent\" data-id=\"97dcced\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;boxed&quot;}\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-dbbdae4 elementor-widget elementor-widget-text-editor\" data-id=\"dbbdae4\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h3>STUDY #1<\/h3><h2>Durasis Dural Graft Yields High Success Rate as Dural Substitute<\/h2><div class=\"elementor-element elementor-element-22381ab e-flex e-con-boxed elementor-repeater-item-default_padding elementor-repeater-item-none elementor-repeater-item-none_hover e-con e-parent e-lazyloaded\" data-id=\"22381ab\" data-element_type=\"container\" data-settings=\"{&quot;ang_container_spacing_size&quot;:&quot;default_padding&quot;,&quot;_ha_eqh_enable&quot;:false}\"><div class=\"e-con-inner\"><div class=\"elementor-element elementor-element-8801b69 elementor-repeater-item-none elementor-repeater-item-none_hover elementor-widget elementor-widget-text-editor\" data-id=\"8801b69\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\"><div class=\"elementor-widget-container\"><strong>Methods:<\/strong> Fifty-nine patients underwent dural reconstruction with the SIS dural substitute. The primary goals of the study were to assess the efficacy and safety of the SIS dural substitute according to the rate of cerebrospinal fluid (CSF) leakage, infection, and meningitis.<\/div><\/div><\/div><\/div>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c99b3c9 e-flex e-con-boxed e-con e-parent\" data-id=\"c99b3c9\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;boxed&quot;}\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-aca6e89 e-con-full e-flex e-con e-child\" data-id=\"aca6e89\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e9cba75 elementor-widget elementor-widget-text-editor\" data-id=\"e9cba75\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<table class=\"table-rules\" width=\"100%\"><thead><tr class=\"ee-table__row\"><th class=\"ee-table__cell elementor-repeater-item-cd4fc25\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">Surgical Site<\/span> <\/span><\/th><th class=\"ee-table__cell elementor-repeater-item-3e6aa31\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">Number of Patients<\/span> <\/span><\/th><\/tr><\/thead><tbody><tr class=\"ee-table__row elementor-repeater-item-ac35c39\"><td class=\"ee-table__cell elementor-repeater-item-5dcc075\" data-title=\"Surgical Site\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">Posterior fossa<\/span> <\/span><\/td><td class=\"ee-table__cell elementor-repeater-item-f570553\" data-title=\"Number of Patients\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">40<\/span> <\/span><\/td><\/tr><tr class=\"ee-table__row elementor-repeater-item-08431ee\"><td class=\"ee-table__cell elementor-repeater-item-0cf64dc\" data-title=\"Surgical Site\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">Frontal<\/span> <\/span><\/td><td class=\"ee-table__cell elementor-repeater-item-a21abe4\" data-title=\"Number of Patients\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">6<\/span> <\/span><\/td><\/tr><tr class=\"ee-table__row elementor-repeater-item-7b27ddd\"><td class=\"ee-table__cell elementor-repeater-item-f120964\" data-title=\"Surgical Site\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">Spinal: cervical<\/span> <\/span><\/td><td class=\"ee-table__cell elementor-repeater-item-317b2d9\" data-title=\"Number of Patients\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">4<\/span> <\/span><\/td><\/tr><tr class=\"ee-table__row elementor-repeater-item-d0cd91a\"><td class=\"ee-table__cell elementor-repeater-item-9979741\" data-title=\"Surgical Site\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">Spinal: thoracic &amp; lumbar<\/span> <\/span><\/td><td class=\"ee-table__cell elementor-repeater-item-8c5f51b\" data-title=\"Number of Patients\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">4<\/span> <\/span><\/td><\/tr><tr class=\"ee-table__row elementor-repeater-item-8cd6663\"><td class=\"ee-table__cell elementor-repeater-item-629aa11\" data-title=\"Surgical Site\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">Frontal\/temporal or temporal<\/span> <\/span><\/td><td class=\"ee-table__cell elementor-repeater-item-59211fc\" data-title=\"Number of Patients\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">3<\/span> <\/span><\/td><\/tr><tr class=\"ee-table__row elementor-repeater-item-b597747\"><td class=\"ee-table__cell elementor-repeater-item-44e9e7b\" data-title=\"Surgical Site\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">Parietal\/occipital or parietal<\/span> <\/span><\/td><td class=\"ee-table__cell elementor-repeater-item-cb5c963\" data-title=\"Number of Patients\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">2<\/span> <\/span><\/td><\/tr><\/tbody><\/table>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-40c0d74 e-con-full e-flex e-con e-child\" data-id=\"40c0d74\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;full&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6693a4d elementor-widget elementor-widget-text-editor\" data-id=\"6693a4d\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<table class=\"table-rules\" width=\"100%\"><thead><tr class=\"ee-table__row\"><th class=\"ee-table__cell elementor-repeater-item-cd4fc25\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">Neurological diagnosis<\/span> <\/span><\/th><th class=\"ee-table__cell elementor-repeater-item-3e6aa31\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">Number of Patients<\/span> <\/span><\/th><\/tr><\/thead><tbody><tr class=\"ee-table__row elementor-repeater-item-ac35c39\"><td class=\"ee-table__cell elementor-repeater-item-5dcc075\" data-title=\"Neurological diagnosis\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">Chiari malformation<\/span> <\/span><\/td><td class=\"ee-table__cell elementor-repeater-item-f570553\" data-title=\"Number of Patients\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">32<\/span> <\/span><\/td><\/tr><tr class=\"ee-table__row elementor-repeater-item-08431ee\"><td class=\"ee-table__cell elementor-repeater-item-0cf64dc\" data-title=\"Neurological diagnosis\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">Tumor\/meningioma<\/span> <\/span><\/td><td class=\"ee-table__cell elementor-repeater-item-a21abe4\" data-title=\"Number of Patients\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">18<\/span> <\/span><\/td><\/tr><tr class=\"ee-table__row elementor-repeater-item-7b27ddd\"><td class=\"ee-table__cell elementor-repeater-item-f120964\" data-title=\"Neurological diagnosis\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">Aneurysm<\/span> <\/span><\/td><td class=\"ee-table__cell elementor-repeater-item-317b2d9\" data-title=\"Number of Patients\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">3<\/span> <\/span><\/td><\/tr><tr class=\"ee-table__row elementor-repeater-item-d0cd91a\"><td class=\"ee-table__cell elementor-repeater-item-9979741\" data-title=\"Neurological diagnosis\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">Spinal cord tethering<\/span> <\/span><\/td><td class=\"ee-table__cell elementor-repeater-item-8c5f51b\" data-title=\"Number of Patients\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">3<\/span> <\/span><\/td><\/tr><tr class=\"ee-table__row elementor-repeater-item-8cd6663\"><td class=\"ee-table__cell elementor-repeater-item-629aa11\" data-title=\"Neurological diagnosis\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">Other<\/span> <\/span><\/td><td class=\"ee-table__cell elementor-repeater-item-59211fc\" data-title=\"Number of Patients\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">3<\/span> <\/span><\/td><\/tr><\/tbody><\/table>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-fa09d1e e-flex e-con-boxed e-con e-parent\" data-id=\"fa09d1e\" data-element_type=\"container\" data-settings=\"{&quot;content_width&quot;:&quot;boxed&quot;}\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-60865c8 elementor-widget elementor-widget-text-editor\" data-id=\"60865c8\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-22381ab e-flex e-con-boxed elementor-repeater-item-default_padding elementor-repeater-item-none elementor-repeater-item-none_hover e-con e-parent e-lazyloaded\" data-id=\"22381ab\" data-element_type=\"container\" data-settings=\"{&quot;ang_container_spacing_size&quot;:&quot;default_padding&quot;,&quot;_ha_eqh_enable&quot;:false}\"><div class=\"e-con-inner\"><div class=\"elementor-element elementor-element-8801b69 elementor-repeater-item-none elementor-repeater-item-none_hover elementor-widget elementor-widget-text-editor\" data-id=\"8801b69\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\"><div class=\"elementor-widget-container\"><div class=\"e-con-inner\"><div class=\"elementor-element elementor-element-85e2cd4 e-con-full e-flex elementor-repeater-item-default_padding elementor-repeater-item-none elementor-repeater-item-none_hover e-con e-child\" data-id=\"85e2cd4\" data-element_type=\"container\" data-settings=\"{&quot;ang_container_spacing_size&quot;:&quot;default_padding&quot;,&quot;_ha_eqh_enable&quot;:false}\"><div class=\"elementor-element elementor-element-7e767a6 ee-table--responsive ee-table-mobile-header--row elementor-repeater-item-none elementor-repeater-item-none_hover elementor-widget elementor-widget-table\" data-id=\"7e767a6\" data-element_type=\"widget\" data-settings=\"{&quot;mobile_headers_auto&quot;:&quot;yes&quot;}\" data-widget_type=\"table.default\"><div class=\"elementor-widget-container\"><div class=\"elementor-element elementor-element-9590e7a ee-table--responsive ee-table-mobile-header--row elementor-repeater-item-none elementor-repeater-item-none_hover elementor-widget elementor-widget-table\" data-id=\"9590e7a\" data-element_type=\"widget\" data-settings=\"{&quot;mobile_headers_auto&quot;:&quot;yes&quot;}\" data-widget_type=\"table.default\"><div class=\"elementor-widget-container\"><div class=\"e-con-inner\"><div class=\"elementor-element elementor-element-7ddb395 elementor-repeater-item-none elementor-repeater-item-none_hover elementor-widget elementor-widget-text-editor\" data-id=\"7ddb395\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\"><div><p><strong>Results:<\/strong> Chiari malformation Type I decompression (32 patients) and tumor resection (18 patients) were the most common procedures performed, with 81% of SIS grafts implanted in the posterior fossa or spine. There was one case of a CSF leak (1.7%), two cases of wound infection (3.4%), and no cases of bacterial meningitis (0%) in the 58 patients available for follow up. In both cases of wound infection, the SIS graft acted as a barrier to infection and was not removed. Intraoperatively, a watertight seal was achieved in all 59 cases. On follow-up imaging available in 27 patients there was no evidence of any adverse reaction to the graft or of cerebral inflammation.<strong>Conclusions:<\/strong> This clinical evaluation of the SIS dural substitute demonstrated that rates of common complications associated with the use of dural substitutes compare favorably to experience reported in the literature with other dural substitute products. There was no evidence of scar tissue formation or encapsulation of the SIS dural substitute. The SIS dural substitute was judged to have excellent handling characteristics, and was associated with a very high rate of device and procedural success. Lack of adverse reactions to the graft, a favorable safety profile, and clinical efficacy all indicate the utility of this material as an alternative for the repair of dural defects.<\/p><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"elementor-element elementor-element-95a858a e-flex e-con-boxed elementor-repeater-item-default_padding elementor-repeater-item-none elementor-repeater-item-none_hover e-con e-parent e-lazyloaded\" data-id=\"95a858a\" data-element_type=\"container\" data-settings=\"{&quot;ang_container_spacing_size&quot;:&quot;default_padding&quot;,&quot;_ha_eqh_enable&quot;:false}\"><div class=\"e-con-inner\"><div class=\"elementor-element elementor-element-1717076 ha-has-bg-overlay elementor-repeater-item-none elementor-repeater-item-none_hover elementor-widget elementor-widget-heading\" data-id=\"1717076\" data-element_type=\"widget\" data-widget_type=\"heading.default\"><div class=\"elementor-widget-container\"><h3 class=\"elementor-heading-title elementor-size-default\">STUDY #2<\/h3><\/div><\/div><div class=\"elementor-element elementor-element-ebe61ad elementor-repeater-item-none elementor-repeater-item-none_hover elementor-widget elementor-widget-heading\" data-id=\"ebe61ad\" data-element_type=\"widget\" data-widget_type=\"heading.default\"><div class=\"elementor-widget-container\"><h2 class=\"elementor-heading-title elementor-size-default\">Retrospective Study Confirms Performance of Biodesign Grafts for Transcranial Dura Mater Repair<\/h2><\/div><\/div><div class=\"elementor-element elementor-element-a4b358b elementor-repeater-item-none elementor-repeater-item-none_hover elementor-widget elementor-widget-text-editor\" data-id=\"a4b358b\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\"><div class=\"elementor-widget-container\"><p><strong>Purpose:<\/strong> The purpose of this study was to assess the real-world performance of the Durasis graft as a dura substitute for repairing dura mater. This report specifically analyzes a subset of patients who underwent transcranial dura mater repairs with the Durasis graft.<\/p><p><strong>Endpoints:<\/strong> The primary endpoint was the postoperative integrity of the graft 1 month after surgery as defined by the lack of need to return to the operating room to repair a cerebrospinal fluid (CSF) leak. Secondary endpoints included postoperative graft integrity at the last available patient follow-up visit (with a minimum of 6 months follow-up) and the assessment of adverse events for normal, widespread use of the graft in the short-term postoperative period. Data were collected from 81 patients at Toronto Western Hospital, Toronto, Ontario, Canada.<\/p><\/div><\/div><\/div><\/div><div class=\"elementor-element elementor-element-86576b9 e-flex e-con-boxed elementor-repeater-item-default_padding elementor-repeater-item-none elementor-repeater-item-none_hover e-con e-parent e-lazyloaded\" data-id=\"86576b9\" data-element_type=\"container\" data-settings=\"{&quot;ang_container_spacing_size&quot;:&quot;default_padding&quot;,&quot;_ha_eqh_enable&quot;:false}\"><div class=\"e-con-inner\"><div class=\"elementor-element elementor-element-97d90f9 e-con-full elementor-repeater-item-none_hover e-flex elementor-repeater-item-default_padding elementor-repeater-item-none e-con e-child\" data-id=\"97d90f9\" data-element_type=\"container\" data-settings=\"{&quot;ang_container_spacing_size&quot;:&quot;default_padding&quot;,&quot;_ha_eqh_enable&quot;:false}\"><div class=\"elementor-element elementor-element-6e52539 ee-table--responsive ee-table-mobile-header--row elementor-repeater-item-none elementor-repeater-item-none_hover elementor-widget elementor-widget-table\" data-id=\"6e52539\" data-element_type=\"widget\" data-settings=\"{&quot;mobile_headers_auto&quot;:&quot;yes&quot;}\" data-widget_type=\"table.default\"><div class=\"elementor-widget-container\"><table class=\"table-rules\" width=\"100%\"><thead><tr class=\"ee-table__row\"><th class=\"ee-table__cell elementor-repeater-item-cd4fc25\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">Primary Endpoints<\/span> <\/span><\/th><th class=\"ee-table__cell elementor-repeater-item-3e6aa31\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">n\/N (percent)<\/span> <\/span><\/th><\/tr><\/thead><tbody><tr class=\"ee-table__row elementor-repeater-item-ac35c39\"><td class=\"ee-table__cell elementor-repeater-item-5dcc075\" data-title=\"Primary Endpoints\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">CSF leak that required a return to the operating room (short-term follow-up, median 46 days)<\/span> <\/span><\/td><td class=\"ee-table__cell elementor-repeater-item-f570553\" data-title=\"n\/N (percent)\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">0\/81 (0%)<\/span> <\/span><\/td><\/tr><tr class=\"ee-table__row elementor-repeater-item-08431ee\"><td class=\"ee-table__cell elementor-repeater-item-0cf64dc\" data-title=\"Primary Endpoints\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">Postoperative CNS infection<\/span> <\/span><\/td><td class=\"ee-table__cell elementor-repeater-item-a21abe4\" data-title=\"n\/N (percent)\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">0\/81 (0%)<\/span> <\/span><\/td><\/tr><tr class=\"ee-table__row elementor-repeater-item-7b27ddd\"><td class=\"ee-table__cell elementor-repeater-item-f120964\" data-title=\"Primary Endpoints\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">Required lumbar drain placement<\/span> <\/span><\/td><td class=\"ee-table__cell elementor-repeater-item-317b2d9\" data-title=\"n\/N (percent)\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">0\/81 (0%)<\/span> <\/span><\/td><\/tr><\/tbody><\/table><\/div><\/div><\/div><div class=\"elementor-element elementor-element-e290b8d e-con-full elementor-repeater-item-none_hover e-flex elementor-repeater-item-default_padding elementor-repeater-item-none e-con e-child\" data-id=\"e290b8d\" data-element_type=\"container\" data-settings=\"{&quot;ang_container_spacing_size&quot;:&quot;default_padding&quot;,&quot;_ha_eqh_enable&quot;:false}\"><div class=\"elementor-element elementor-element-415807f ee-table--responsive ee-table-mobile-header--row elementor-repeater-item-none elementor-repeater-item-none_hover elementor-widget elementor-widget-table\" data-id=\"415807f\" data-element_type=\"widget\" data-settings=\"{&quot;mobile_headers_auto&quot;:&quot;yes&quot;}\" data-widget_type=\"table.default\"><div class=\"elementor-widget-container\"><table class=\"table-rules\" width=\"100%\"><thead><tr class=\"ee-table__row\"><th class=\"ee-table__cell elementor-repeater-item-cd4fc25\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">Secondary Endpoints<\/span> <\/span><\/th><th class=\"ee-table__cell elementor-repeater-item-3e6aa31\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">n\/N (percent)<\/span> <\/span><\/th><\/tr><\/thead><tbody><tr class=\"ee-table__row elementor-repeater-item-ac35c39\"><td class=\"ee-table__cell elementor-repeater-item-5dcc075\" data-title=\"Secondary Endpoints\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">CSF leak that required a return to the operating room (mid-term follow-up, median 175 days)<\/span> <\/span><\/td><td class=\"ee-table__cell elementor-repeater-item-f570553\" data-title=\"n\/N (percent)\"><span class=\"ee-table__text\"><span class=\"ee-table__text__inner\">0\/72 (0%)<\/span> <\/span><\/td><\/tr><\/tbody><\/table><\/div><\/div><\/div><\/div><\/div><div class=\"elementor-element elementor-element-fcfbc0b e-flex e-con-boxed elementor-repeater-item-default_padding elementor-repeater-item-none elementor-repeater-item-none_hover e-con e-parent e-lazyloaded\" data-id=\"fcfbc0b\" data-element_type=\"container\" data-settings=\"{&quot;ang_container_spacing_size&quot;:&quot;default_padding&quot;,&quot;_ha_eqh_enable&quot;:false}\"><div class=\"e-con-inner\"><div class=\"elementor-element elementor-element-de2ec2c elementor-repeater-item-none elementor-repeater-item-none_hover elementor-widget elementor-widget-text-editor\" data-id=\"de2ec2c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\"><div class=\"elementor-widget-container\"><p><strong>Study Results:<\/strong> No unexpected or serious adverse events were reported among the 81 patients in the study, and no patients examined were returned to the operating room for a postoperative CSF leak. Of the 10 patients reporting complications, CSF leak (not requiring reoperation) (n=2, 2.5%), and wound infection(n=2, 2.5%) were the most frequently reported complications. None of these complications were considered unexpected or serious. They were also not reported to be device related.<\/p><\/div><\/div><\/div><\/div><div class=\"elementor-element elementor-element-f584491 e-flex e-con-boxed elementor-repeater-item-default_padding elementor-repeater-item-none elementor-repeater-item-none_hover e-con e-parent e-lazyloaded\" data-id=\"f584491\" data-element_type=\"container\" data-settings=\"{&quot;ang_container_spacing_size&quot;:&quot;default_padding&quot;,&quot;_ha_eqh_enable&quot;:false}\"><div class=\"e-con-inner\"><div class=\"elementor-element elementor-element-7d71f80 elementor-repeater-item-none elementor-repeater-item-none_hover elementor-widget elementor-widget-text-editor\" data-id=\"7d71f80\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\"><div class=\"elementor-widget-container\"><strong>Conclusion:<\/strong> No unexpected adverse events were reported during this clinical study in this subset of patients. The analysis confirms the safety and effectiveness of the Durasis graft for dura mater repair. These results support its continued use in accordance with the labeled indication. Further data from ongoing studies will contribute to the long-term assessment of the graft\u2019s performance and safety.<\/div><\/div><\/div><\/div><div class=\"elementor-element elementor-element-8ecf04b e-flex e-con-boxed elementor-repeater-item-default_padding elementor-repeater-item-none elementor-repeater-item-none_hover e-con e-parent e-lazyloaded\" data-id=\"8ecf04b\" data-element_type=\"container\" data-settings=\"{&quot;ang_container_spacing_size&quot;:&quot;default_padding&quot;,&quot;_ha_eqh_enable&quot;:false}\"><div class=\"e-con-inner\"><div class=\"elementor-element elementor-element-80d2169 e-con-full elementor-repeater-item-none_hover e-flex elementor-repeater-item-default_padding elementor-repeater-item-none e-con e-child\" data-id=\"80d2169\" data-element_type=\"container\" data-settings=\"{&quot;ang_container_spacing_size&quot;:&quot;default_padding&quot;,&quot;_ha_eqh_enable&quot;:false}\"><div class=\"elementor-element elementor-element-552768b elementor-repeater-item-none elementor-repeater-item-none_hover elementor-widget elementor-widget-heading\" data-id=\"552768b\" data-element_type=\"widget\" data-widget_type=\"heading.default\"><div class=\"elementor-widget-container\"><h3 class=\"elementor-heading-title elementor-size-default\">Summary<\/h3><\/div><\/div><div class=\"elementor-element elementor-element-1358878 elementor-repeater-item-none elementor-repeater-item-none_hover elementor-widget elementor-widget-text-editor\" data-id=\"1358878\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\"><div class=\"elementor-widget-container\"><p>Durasis grafts support the repair of dura mater by providing a conducive environment in which the body\u2019s cells can attach, proliferate, and differentiate to restore organized, remodeled tissue.\u00a0At the same time, the graft is slowly replaced during the normal process of collagen turnover such that no graft material remains after this process is complete.<\/p><p>Compared to other surgical treatments of dura mater repair, there are several benefits associated with the use of Durasis SIS.<\/p><\/div><\/div><div class=\"elementor-element elementor-element-f614be8 elementor-repeater-item-none elementor-repeater-item-none_hover elementor-widget elementor-widget-heading\" data-id=\"f614be8\" data-element_type=\"widget\" data-widget_type=\"heading.default\"><div class=\"elementor-widget-container\"><h3 class=\"elementor-heading-title elementor-size-default\">Identified benefits of Durasis SIS grafts in dura mater repair<\/h3><\/div><\/div><div class=\"elementor-element elementor-element-e5f6605 elementor-repeater-item-none elementor-repeater-item-none_hover elementor-widget elementor-widget-text-editor\" data-id=\"e5f6605\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\"><div class=\"elementor-widget-container\"><ul><li>No donor site required and no donor site morbidity<\/li><li>Easy to handle and suture, allowing for a watertight seal<\/li><li>Provides the strength required for a durable repair<\/li><li>Functions as a scaffold for the ingrowth of host cells for a natural repair<\/li><li>Produces little to no scar formation<\/li><li>Does not swell upon hydration<\/li><li>Provides a leak-free repair<\/li><\/ul><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Seal the Deal with an Intact Biological Graft. DURASIS\u2122 DURAL GRAFT The Durasis Dural Graft is intended for use as a dura substitute for repairing dura mater. Nexsis Biosciences is the exclusive U.S. and Canadian supplier of the Durasis Dural Graft (formerly Cook Biotech\u2019s Biodesign\u00ae Dural Graft). Durasis\u2122 Dural Graft ORDER NUMBER DESCRIPTION INSTRUCTIONS FOR [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2671,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7,32],"tags":[],"class_list":["post-2667","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-neurosurgery","category-nexsis-biosciences"],"_links":{"self":[{"href":"https:\/\/surgi-one.com\/main\/wp-json\/wp\/v2\/posts\/2667","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/surgi-one.com\/main\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/surgi-one.com\/main\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/surgi-one.com\/main\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/surgi-one.com\/main\/wp-json\/wp\/v2\/comments?post=2667"}],"version-history":[{"count":43,"href":"https:\/\/surgi-one.com\/main\/wp-json\/wp\/v2\/posts\/2667\/revisions"}],"predecessor-version":[{"id":2813,"href":"https:\/\/surgi-one.com\/main\/wp-json\/wp\/v2\/posts\/2667\/revisions\/2813"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/surgi-one.com\/main\/wp-json\/wp\/v2\/media\/2671"}],"wp:attachment":[{"href":"https:\/\/surgi-one.com\/main\/wp-json\/wp\/v2\/media?parent=2667"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/surgi-one.com\/main\/wp-json\/wp\/v2\/categories?post=2667"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/surgi-one.com\/main\/wp-json\/wp\/v2\/tags?post=2667"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}