The synthetic P-15 peptide results in early bone formation and fusion in a pre-clinical spine model.

The synthetic P-15 peptide results in greater tissue volume fraction and thicker trabeculae compared to autograft in the sheep femur.

The synthetic P-15 peptide accelerates bone regeneration in a pre-clinical osteoporotic rat model.

The synthetic P-15 peptide enhances bone formation compared to non-treated anorganic bone (hydroxyapatite) in posterolateral fusion.

  • Axelsen MG, et al. Evaluation of cell binding peptide (P15) with silk fibre enhanced hydroxyapatite bone substitute for posterolateral spinal fusion in sheep, Eurospine 2015 Annual Meeting, Poster #30

The synthetic P-15 peptide results in significantly faster bone formation in pre-clinical long bone defects.

The synthetic P-15 peptide results in significantly faster bone formation in pre-clinical cranial model.

The synthetic P-15 peptide results in more bone growth compared to non-treated anorganic bone mineral (hydroxyapatite) in a rabbit osseous defect.

  • Guerra FA, et al. Small peptide (P-15) bone substitute efficacy in a rabbit cancellous bone model, ORS 2005 Annual Meeting, Poster #0212

The synthetic P-15 peptide results in equivalent fusion rates to autologous bone in an ovine lumbar fusion model.

  • Patel VV, et al. Lumbar spine fusion in an ovine model comparing P-15/BGS to autogenous bone, ORS 2007 Annual Meeting, Poster #1452

The synthetic P-15 peptide results in superior fusion rates compared to autograft in a goat cervical fusion model.

  • Cheng BC, et al. P-15: An osteoconductive protein to enhance healing of interbody cages, ORS 1998 Annual Meeting, Poster #636

The synthetic P-15 peptide results in optimal healing of segmental cortical bone defects in a rat model.

The synthetic P-15 peptide results in enhanced new bone formation in cortical defects in a rabbit model.

The synthetic P-15 peptide results in faster new bone formation in maxillary sinus defects compared to allograft.

The synthetic P-15 peptide enhances fusion in the  demanding periodontal environment.